Van de Ven Brace Ends The Toffees' Unbeaten Streak at New Stadium
The Dutch defender emerged as the first backline player to net two goals in a English top-flight game for Tottenham since Jan Vertonghen in spring 2013.
Match summary
Micky Van de Ven nods into the net twice in first half
Everton's defender has goal ruled after VAR review
Senegalese midfielder nets final goal in dying moments
The defeat is the Merseyside club's initial at their new ground
The Tottenham defender scored twice as Tottenham prolonged their winning streak in away games in the top division and handed Everton their initial loss at their new home.
Everton were undefeated in their last five matches at their new ground at Bramley-Moore Dock, having left their historic home behind after 133 years at the conclusion of the previous campaign.
But Tottenham's leader the Dutchman struck twice from set-pieces in the first half to put their impressive record at jeopardy, and they were failed to turn it around before Pape Matar Sarr - assisted by former Toffees attacker Richarlison - headed home a third to seal the victory.
Jake O'Brien thought he had levelled the scores five minutes after the defender's first goal, glancing a bullet header past the Spurs keeper from an Everton corner.
Beto, meanwhile, missed a number of chances, while the Italian goalkeeper made a series of excellent stops to guarantee the London club went five matches on the road without defeat in the English top flight.
But the video assistant referee stepped in, instructing the match official to review the score on the pitchside monitor and the referee decided that the winger and Iliman Ndiaye were in an illegal position and had interfered with the Tottenham goalkeeper.
This victory moves Thomas Frank's side into third place in the Premier League, five points off local foes and table-toppers Arsenal.
Everton stay in 14th position and are six points ahead of the relegation zone.
Tottenham analysis: Van de Ven fulfils duties at each end of pitch
Following a drab weekday performance in the Champions League against Monaco, where they mustered a mere two shots on goal, Frank opted for Randal Kolo Muani up front instead of former Toffees player the Brazilian.
The summer signing was failed to influence the game before being replaced for the substitute after 60 minutes on the pitch, but it emerged he proved unnecessary in the final outcome.
Centre-back the Dutchman transformed into an offensive threat to be feared.
Tottenham's opening strike came from a cleverly executed set-piece play, with the midfielder directing the ball toward the six-yard box for an free Van de Ven to score.
And Ven de Ven - stepping up as captain in Cristian Romero's absence - notched his second in added time as he outjumped the England keeper to head home.
Van de Ven was equally impressive in defensive duties, combining well with Kevin Danso as the pair dealt superbly with the 34 crosses thrown their way by Everton.
Toffees breakdown: Everton lacking striker's instinct
The club's new home had been a happy hunting ground, but it appears the novelty may have worn off somewhat and supporters flocked to the exits after Sarr's final goal for Tottenham.
The end in Everton's winning streak at home won't be a major worry for the manager, but their striker situation will be.
The forward and the other striker - the Everton's pair of established centre-forwards - had netted only one league goal combined before Sunday's outing.
And they were unable to add to that poor record on a damp and dreary night on in Liverpool.
The striker's performance was epitomized when he chose to overhead kick a golden opportunity from near the goal, despite having room and opportunity to reposition for a more conventional attempt that would have tested Vicario.
Barry, as well, failed to influence the game after coming on for the starter in the 65th minute.
It was not for a shortage of chance. Most of Everton's offensive moves came through Grealish and Ndiaye, who relentlessly whipped dangerous crosses into the Tottenham penalty area.
Upcoming fixtures for both teams?
The Toffees: The team travel to the Stadium of Light in the top flight on Monday, 3 November at 8 PM.
Spurs: Spurs travel to Newcastle's ground on late October for their next round League Cup match against the Magpies.